Alzheimer’s and Parkinson’s

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Alzheimer’s and Parkinson’s

What are neurodegenerative diseases?
The ketogenic diet has been shown to improve and balances out insulin levels, sex hormones (decrease free testosterone and increases sex-hormone binding globulin), and Neurodegenerative diseases are a group of conditions that cause deterioration of the brain. This leads to symptoms including memory loss, motor difficulties, behavioral changes, and decreased cognitive functioning. This month we will be focusing on the two following neurodegenerative diseases: Alzheimer’s and Parkinsons.

What is Alzheimer’s and Parkinson’s disease?
Alzheimer’s disease (AD) is a progressive form of dementia that leads to memory loss and decreases in cognitive functioning. While the exact mechanism of AD is not well understood, the most widely accepted theory is the accumulation of beta-amyloid proteins. These proteins clog up the brain and lead to decreased neural transmission and death.
Parkinson’s disease (PD) is another progressive neurodegenerative disease, but is characterized by motor dysfunction. PD is caused by the death of dopaminergic neurons within the substantia nigra and basal ganglia of the brain. Dopamine is a neurotransmitter vital for motor movement and thus low dopamine concentrations lead to tremors, bradykinesia (slow movement), difficulty moving, and more.

How can the ketogenic diet help individuals with neurodegenerative diseases?

Recent research has identified a potential mechanism behind some of the cognitive decline experienced in neurodegenerative disease: limited glucose uptake within the brain. In fact, many are calling Alzheimer’s Disease type 3 diabetes because of the drastic reduction of glucose within the brain. Since the ketogenic diet causes an increase in ketone levels which provides an alternative fuel source that readily crosses the blood-brain-barrier and uses a transportation system different from glucose (M.C.T.s vs GLUTS), the brain does not experience a limited energy supply. Studies have shown the ketogenic diet drastically improve cognitive functioning, memory, and coordination in individuals with neurodegenerative diseases. They results may be further amplified when coupled with exogenous ketone or MCT/coconut oil supplementation.

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Articles

Research

Low-fat versus ketogenic diet in Parkinson's disease: A pilot randomized controlled trial.

The Expanding Role of Ketogenic Diets in Adult Neurological Disorders

The efficacy of the ketogenic diet on motor functions in Parkinson’s disease: A rat model

Neuroprotective and disease-modifying effects of the ketogenic diet

How Can a Ketogenic Diet Improve Motor Function?

Role of Ketogenic Diets in Neurodegenerative Diseases (Alzheimer’s Disease and Parkinson’s Disease)

Effects of a medium-chain triglyceride-based ketogenic formula on cognitive function in patients with mild-to-moderate Alzheimer's disease.

Ketogenic diet in neuromuscular and neurodegenerative diseases.

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