If using a well-formulated ketogenic diet, then no; not only is the high amount of fat on a ketogenic diet satiating, but ketones also seem to reduce hunger signals. Studies have allowed subjects on a ketogenic diet to eat as much as they want, yet they still tend to eat fewer calories, report less hunger, and lose more weight than those on a non-ketogenic diet . It is possible that this is because fat is more calorically dense; however, studies have also demonstrated that being in a state of ketosis can reduce hunger signals.