- “A low-carbohydrate, ketogenic diet extends longevity in adult male mice. Motor function, memory, and muscle mass are preserved in aged ketogenic mice.”
- “Ketone bodies have signaling functions as well as being a mobile source of cellular energy. Ketone bodies inhibit histone deacetylases and control gene transcription. Histone deacetylase function is implicated in the regulation of aging.”
- “Lifelong KD improves longevity in rats without altering body mass and our data show that the longevity benefits of KD come without altering oxidative damage or antioxidant protein levels in the gastrocnemius, liver, or brain.”
I won’t sit here and say that being in a state of ketosis is going to make you live forever, but I’m confident that being on a well-formulated ketogenic diet hasn’t been shown to accelerate aging, and no mechanisms would point to why that would be the case – if anything, it’s the opposite.